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Future-proofing livestock vaccines by anticipating viruses" next moves
8+ hour, 39+ min ago (1181+ words) The video is still processing. Please wait a few minutes. Ratul Chowdhury describes his working using AI tools to develop livestock vaccines. Ratul Chowdhury, an assistant professor of chemical and biological engineering at Iowa State University, develops livestock vaccines built…...
Novel SOAT inhibitors block DHEAS transport and suppress proliferation in MCF-7 breast cancer cells - Scientific Reports
57+ min ago (150+ words) Statistical analyses were performed using Graph Pad Prism 6. 07 (Graph Pad Software, La Jolla, CA, USA). One-way ANOVA was used to analyze differences between groups, and two-way ANOVA was used to evaluate the results of steroid profiling. Data are presented as…...
Single-Cell Map Reveals Immune Crosstalk in Cholangitis
1+ hour, 37+ min ago (821+ words) In a groundbreaking study reshaping our understanding of immune interactions within the liver's biliary system, Thomann, Hemmer, Agrawal, and colleagues have unveiled an unprecedented single-cell atlas that deciphers the intricate dialogue between type 2 conventional dendritic cells (c DC2s) and " T cells…...
Astrocytic apelin mediates cortical neuronal function and prevents anxiety-like behaviors in mice - Acta Pharmacologica Sinica
1+ hour, 52+ min ago (1339+ words) Boucher J, Masri B, Daviaud D, Gesta S, Guign" C, Mazzucotelli A, et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology. 2005; 146: 176471. Kuba K, Zhang L, Imai Y, Arab S, Chen M, Maekawa Y, et al. Impaired…...
MARCH2 Guards Heart by Stabilizing NR1 H2, Clearing Cells
4+ hour, 50+ min ago (298+ words) The research community is now faced with exciting questions: Can small molecules be developed to enhance MARCH2 function or stabilize NR1 H2 in the human heart? Will these interventions prove effective and safe in clinical settings? Furthermore, could this pathway be relevant in…...
Naturally Occurring Bacteria Completely Eradicate Tumors in Mice With a Single Dose
5+ hour, 27+ min ago (204+ words) A bacterium from frog gut microbiota eliminated tumors in mice by selectively colonizing tumors and triggering both direct cell killing and immune-driven anticancer responses. Further analysis revealed that E. americana targets cancer through two coordinated biological actions that work together to…...
Vaccine Sparks HIV-Fighting Antibodies in Edited Primates
6+ hour, 26+ min ago (1318+ words) Bioengineer. org In a groundbreaking advance poised to reshape the future of HIV vaccination strategies, researchers have successfully demonstrated that genome-edited B cells can be coaxed into producing broadly neutralizing antibodies (bn Abs) against HIV in non-human primate models. This…...
Core structure of Borna disease virus 1
8+ hour, 18+ min ago (27+ words) (IMAGE)Eurek Alert! Overview of this study More on this News Release Unraveling the complexities of the Borna disease virus 1...
New BSC Study Uncovers Significant Age-Related Changes in the Female Immune
10+ hour, 54+ min ago (1231+ words) System Compared to Males'Bioengineer. org In a groundbreaking study conducted at the Barcelona Supercomputing Center " Centro Nacional de Supercomputaci'n (BSC-CNS), new insights into the aging human immune system have emerged, revealing that immunosenescence unfolds differently in men and women at…...
Rapid CAR screening and circ RNA-driven CAR-NK cells for persistent shed-resistant immunotherapy - Signal Transduction and Targeted Therapy
22+ hour, 39+ min ago (1759+ words) NSG mice and BALB/c nude mice were purchased from JABIO (Gyeonggi-do, Korea). BALB/c mice were purchased from KOATECH (Gyeonggi-do, Korea). Male mice aged 68 weeks were randomly assigned to experimental groups for the study. All the data are expressed…...
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